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pentobarbital will decrease the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.pentobarbital will lessen the level or effect of eltrombopag by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep track of.Check Closely (1)pentobarbital will lower the level or resu